LY2811376 [1194044-20-6]

TargetMol Chemicals

LY2811376 [1194044-20-6]

9

1194044-20-6

Chemical

Research Use Only

LY2811376

99.01%

C15H14F2N4S

320.36

LY2811376, an orally available non-peptidic beta-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Abeta secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including pepsin, cathepsin D, or renin.

3 years

C[C@]1(CCSC(N)=N1)c1cc(c(F)cc1F)-c1cncnc1

-20°C

12352200