Chemical Structure
Chemical Structure
LY2835219 [1231930-82-7]
CDX-L0303
CAS Number1231930-82-7
Product group Chemicals
Estimated Purity>99%
Molecular Weight602.7
Overview
- SupplierChemodex
- Product NameLY2835219 [1231930-82-7]
- Delivery Days Customer10
- CAS Number1231930-82-7
- CertificationResearch Use Only
- Estimated Purity>99%
- Hazard InformationWarning
- Molecular FormulaC27H32F2N8 . CH4O3S
- Molecular Weight602.7
- Scientific DescriptionChemical. CAS: 1231930-82-7. Formula: C27H32F2N8 . CH4O3S. MW: 602.7. LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds. - LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.
- SMILESCCN(CC1)CCN1CC2=CC=C(NC3=NC=C(F)C(C4=CC(F)=C(N=C(C)N5C(C)C)C5=C4)=N3)N=C2.CS(=O)(O)=O
- Storage InstructionRT
- UNSPSC12352200