LY367385

MedChem Express

LY367385 [198419-91-9]

10

198419-91-9

Research Use Only

99.0

C10H11NO4

209.20

LY367385 is a highly selective and potent mGluR1a antagonist. LY367385 has an IC 50 of 8.8 microM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 microM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects [1] [2] .

OC([C@H](C1=C(C=C(C(O)=O)C=C1)C)N)=O

-20°C,2°C to 8°C

12352200