LY367385

Biorbyt

LY367385

10

198419-91-9

Research Use Only

C10H11NO4

209.198643

LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC50 of 8.8 microM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 microM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects.

OC([C@H](C1C=CC(C(=O)O)=CC=1C)N)=O

12352200