LYN (phospho Tyr397) antibody detects LYN (phospho Tyr397) protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse tissues. LYN (phospho Tyr397) stained by LYN (phospho Tyr397) antibody (GTX635694) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
![Untreated (–) and treated (+) Raji whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with LYN (phospho Tyr397) antibody [HL122] (GTX635694) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX635694/GTX635694_44683_20220520_WB_treatment_pervanadate_23013122_283.webp "Untreated (–) and treated (+) Raji whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with LYN (phospho Tyr397) antibody [HL122] (GTX635694) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![LYN (phospho Tyr397) antibody [HL122] detects LYN (phospho Tyr397) protein in the occipital lobe of human Alzheimer's disease brain by immunohistochemical analysis. Sample: Paraffin-embedded Human Matched Pair Tissue Array - Brain (Alzheimer's Disease + Normal) (GTX49382). LYN (phospho Tyr397) stained by LYN (phospho Tyr397) antibody [HL122] (GTX635694) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX635694/GTX635694_44027_20220218_IHC-P_w_23061202_348.webp "LYN (phospho Tyr397) antibody [HL122] detects LYN (phospho Tyr397) protein in the occipital lobe of human Alzheimer's disease brain by immunohistochemical analysis. Sample: Paraffin-embedded Human Matched Pair Tissue Array - Brain (Alzheimer's Disease + Normal) (GTX49382). LYN (phospho Tyr397) stained by LYN (phospho Tyr397) antibody [HL122] (GTX635694) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Untreated (–) and treated (+) Raji whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with LYN (phospho Tyr397) antibody [HL122] (GTX635694) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX635694/GTX635694_44027_20220128_WB_treatment_Pervanadate_peptideblocking_w_23061202_906.webp "Untreated (–) and treated (+) Raji whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with LYN (phospho Tyr397) antibody [HL122] (GTX635694) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.")
![Specificity test was performed by coating the plate with recombinant LYN non-phospho peptide, LYN (phospho Tyr397) peptide, Lck non-phospho peptide, Lck (phospho Tyr394) peptide, FYN non-phospho peptide, FYN (phospho Tyr420) peptide, Src non-phospho peptide, Src (phospho 419) peptide, c-Yes non-phospho peptide and c-Yes (phospho Tyr226) peptide (62.5 ng/mL). Coated protein was probed with LYN (phospho Tyr397) antibody [HL122] (GTX635694) (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect the bound primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX635694/GTX635694_45138_20251031_ELISA_Indirect_Multiple_Bar_Specificity_25110619_127.webp "Specificity test was performed by coating the plate with recombinant LYN non-phospho peptide, LYN (phospho Tyr397) peptide, Lck non-phospho peptide, Lck (phospho Tyr394) peptide, FYN non-phospho peptide, FYN (phospho Tyr420) peptide, Src non-phospho peptide, Src (phospho 419) peptide, c-Yes non-phospho peptide and c-Yes (phospho Tyr226) peptide (62.5 ng/mL). Coated protein was probed with LYN (phospho Tyr397) antibody [HL122] (GTX635694) (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect the bound primary antibody.")
LYN (phospho Tyr397) antibody detects LYN (phospho Tyr397) protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse tissues. LYN (phospho Tyr397) stained by LYN (phospho Tyr397) antibody (GTX635694) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
LYN (phospho Tyr397) antibody [HL122]
GTX635694
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetLYN
Overview
- SupplierGeneTex
- Product NameLYN (phospho Tyr397) antibody [HL122]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL122
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4067
- Target nameLYN
- Target descriptionLYN proto-oncogene, Src family tyrosine kinase
- Target synonymsJTK8, SAIDV, p53Lyn, p56Lyn, tyrosine-protein kinase Lyn, lck/Yes-related novel protein tyrosine kinase, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
- HostRabbit
- IsotypeIgG
- Protein IDP07948
- Protein NameTyrosine-protein kinase Lyn
- Scientific DescriptionThis gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Munshi M, Liu X, Kofides A, et al. A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas. Blood Adv. 2022,6(11):3332-3338. doi: 10.1182/bloodadvances.2021006147Read this paper
Datasheet
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