MAD1 antibody
GTX105079
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMAD1L1
Overview
- SupplierGeneTex
- Product NameMAD1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8379
- Target nameMAD1L1
- Target descriptionmitotic arrest deficient 1 like 1
- Target synonymsMAD1, MVA7, PIG9, TP53I9, TXBP181, mitotic spindle assembly checkpoint protein MAD1, MAD1 mitotic arrest deficient like 1, MAD1-like protein 1, mitotic arrest deficient 1-like protein 1, mitotic checkpoint MAD1 protein homolog, mitotic-arrest deficient 1, yeast, homolog-like 1, tax-binding protein 181, tumor protein p53 inducible protein 9
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6D9
- Protein NameMitotic spindle assembly checkpoint protein MAD1
- Scientific DescriptionMAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Sobajima T, Kowalczyk KM, Skylakakis S, et al. PP6 regulation of Aurora A-TPX2 limits NDC80 phosphorylation and mitotic spindle size. J Cell Biol. 2023,222(5). doi: 10.1083/jcb.202205117Read this paper
- Chen L, Ouyang YC, Gu LJ, et al. Septin 9 controls CCNB1 stabilization via APC/C(CDC20) during meiotic metaphase I/anaphase I transition in mouse oocytes. Cell Prolif. 2023,56(2):e13359. doi: 10.1111/cpr.13359Read this paper
- Chen Q, Zhang M, Pan X, et al. Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation. Cell Rep. 2021,36(12):109740. doi: 10.1016/j.celrep.2021.109740Read this paper
- Geraghty Z, Barnard C, Uluocak P, et al. The association of Plk1 with the astrin-kinastrin complex promotes formation and maintenance of a metaphase plate. J Cell Sci. 2021,134(1). doi: 10.1242/jcs.251025Read this paper
- Hayward D, Bancroft J, Mangat D, et al. Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56. J Cell Biol. 2019,218(10):3188-3199. doi: 10.1083/jcb.201905026Read this paper
- Alfonso-Pérez T, Hayward D, Holder J, et al. MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling. J Cell Biol. 2019,218(4):1108-1117. doi: 10.1083/jcb.201808015Read this paper
- Hayward D, Alfonso-Pérez T, Cundell MJ, et al. CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization. J Cell Biol. 2019,218(4):1182-1199. doi: 10.1083/jcb.201808014Read this paper
Datasheet
Related products
Product group Antibodies
Phospho-MAD1L1 (S428) AntibodyCSB-PA060282
ApplicationsELISA, ImmunoHistoChemistry
ReactivityHuman
TargetMAD1L1
- SizePrice
Product group Antibodies
MAD1 antibodyGTX32710
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetMAD1L1
- SizePrice
Product group Antibodies
MAD1 antibody [9B10]GTX48641
ApplicationsImmunoPrecipitation, Western Blot, ELISA
TargetMAD1L1
- SizePrice
Product group Antibodies
Anti-MAD1L1 Antibody144-01153
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
TargetMAD1L1
- SizePrice
Product group Antibodies
Anti-MAD1/MAD1L1 Antibody Picoband(r)PB9262-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetMAD1L1
- SizePrice
Product group Antibodies
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetMAD1L1
- SizePrice
Product group Antibodies
MAD1 Recombinant AntibodyBSM-62140R
ApplicationsWestern Blot
TargetMAD1L1
- SizePrice
Product group Antibodies
References
MAD1 antibodyGTX109519
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetMAD1L1
- SizePrice