IHC-P analysis of human tonsil tissue section using GTX02671 MALT1 antibody [MT1/3159R].
IHC-P analysis of human tonsil tissue section using GTX02671 MALT1 antibody [MT1/3159R].
MALT1 antibody [MT1/3159R]
GTX02671
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMALT1
Overview
- SupplierGeneTex
- Product NameMALT1 antibody [MT1/3159R]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMT1/3159R
- Concentration200 ug/ml
- ConjugateUnconjugated
- Gene ID10892
- Target nameMALT1
- Target descriptionMALT1 paracaspase
- Target synonymscaspase-like protein; IMD12; MALT1 protease; MLT; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase-1; PCASP1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203