Mannose Receptor antibody [15-2] (Low Endotoxin)
GTX00491-00
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMRC1
Overview
- SupplierGeneTex
- Product NameMannose Receptor antibody [15-2] (Low Endotoxin)
- Delivery Days Customer9
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID15-2
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4360
- Target nameMRC1
- Target descriptionmannose receptor C-type 1
- Target synonymsbA541I19.1; CD206; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; hMR; human mannose receptor; macrophage mannose receptor 1; macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1-like 1; MMR; MRC1L1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats. Han GH et al., 2021 Jun, Cell ProlifRead more