Western blot analysis of extracts from MDA cells using MKK3(Ab-189) Antibody.
Western blot analysis of extracts from MDA cells using MKK3(Ab-189) Antibody.
MAP2K3 (Ab-189) Antibody
CSB-PA563519
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMAP2K3
Overview
- SupplierCusabio
- Product NameMAP2K3 (Ab-189) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5606
- Target nameMAP2K3
- Target descriptionmitogen-activated protein kinase kinase 3
- Target synonymsdual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3; MEK 3; MEK3; MKK3; PRKMK3; SAPK kinase 2; SAPKK2; SAPKK-2; stress-activated protein kinase kinase 2
- HostRabbit
- IsotypeIgG
- Protein IDP46734
- Protein NameDual specificity mitogen-activated protein kinase kinase 3
- Scientific DescriptionMEK3 belongs to MAPKK family. This kinase is activated by mitogenic and environmental stress, and participates in the MAPK-mediated signaling cascade. It phosphorylates and thus activates p38. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of Ras oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of p38, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Wang W, et al. (2002) Mol Cell Biol ; 22(10): 3389-403. Raingeaud J, et al. (1996) Mol Cell Biol; 16(3): 1247-55.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203