The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA255018(MAP3K7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
MAP3K7 Antibody
CSB-PA255018
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMAP3K7
Overview
- SupplierCusabio
- Product NameMAP3K7 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6885
- Target nameMAP3K7
- Target descriptionmitogen-activated protein kinase kinase kinase 7
- Target synonymsCSCF; FMD2; MEKK7; mitogen-activated protein kinase kinase kinase 7; TAK1; TGF1a; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1
- HostRabbit
- IsotypeIgG
- Protein IDO43318
- Protein NameMitogen-activated protein kinase kinase kinase 7
- Scientific DescriptionThe protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203