Western Blot analysis of Human lymphoma and liver cancer tissue using JNK1 Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of Human lymphoma and liver cancer tissue using JNK1 Polyclonal Antibody at dilution of 1:1000
MAPK8 Polyclonal Antibody
E-AB-12525
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMAPK8 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
- UNSPSC12352203