Marizomib

MedChem Express

Marizomib [437742-34-2]

5

437742-34-2

Research Use Only

99.13

C15H20ClNO4

313.78

Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrant, pan-proteasome inhibitor. Marizomib inhibits the CT-L (beta5), CT-T-laspase-like (C-L, beta1) and trypsin-like (T-L, beta2) activities of the 20S proteasome (IC 50 =3.5, 28, and 430 nM, respectively) [1] [2] [3] .

O=C([C@H](CCCl)[C@]1(C)O2)N[C@@]1([C@H]([C@@H]3C=CCCC3)O)C2=O

-20°C,2°C to 8°C

12352200