MART-1 / Melan-A(M2-7C10 + M2-9E3), Biotin conjugate, 0.1mg/mL [26628-22-8]

Biotium

MART-1 / Melan-A(M2-7C10 + M2-9E3), Biotin conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

M2-7C10 M2-9E3

0.1 mg/ml

Biotin

MLANA

melan-A

antigen LB39-AA; antigen SK29-AA; epididymis secretory sperm binding protein; MART1; MART-1; melanoma antigen recognized by T-cells 1; protein Melan-A

Mouse

IgG

Melanoma antigen recognized by T-cells 1

This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse, Rat

2°C to 8°C

12352203