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Mast cell chymase antibody [CC1]

Research Use Only
GTX72388
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCMA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Mast cell chymase antibody [CC1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CC1
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID1215
  • Target name
    CMA1
  • Target description
    chymase 1
  • Target synonyms
    alpha-chymase; chymase; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I; chymase 1, mast cell; chymase, heart; chymase, mast cell; CYH; mast cell protease I; MCT1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP23946
  • Protein Name
    Chymase
  • Scientific Description
    This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy. Buckley CL et al., 2011 Jul-Aug, Channels (Austin)
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