Mast cell chymase antibody [CC1]
GTX75583
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCMA1
Overview
- SupplierGeneTex
- Product NameMast cell chymase antibody [CC1]
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCC1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1215
- Target nameCMA1
- Target descriptionchymase 1
- Target synonymsalpha-chymase; chymase; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I; chymase 1, mast cell; chymase, heart; chymase, mast cell; CYH; mast cell protease I; MCT1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy. Buckley CL et al., 2011 Jul-Aug, Channels (Austin)Read more