Mavelertinib

MedChem Express

Mavelertinib [1776112-90-3]

10

1776112-90-3

Research Use Only

99.34

C18H22FN9O2

415.42

Mavelertinib is a selective, orally available and irreversible EGFR tyrosine kinase inhibitor (EGFR TKI) , with IC 50 s of 5, 4, 12 and 3 nM for Del, L858R, and double mutants T790M/L858R and T790M/Del, respectively. Mavelertinib can be used for the research of non-small-cell lung cancer (NSCLC) [1] [2] [3] [4] .

C=CC(N[C@@H]1CN(C2=NC(NC3=CN(C)N=C3OC)=C4N=CN(C)C4=N2)C[C@H]1F)=O

-20°C,2°C to 8°C

12352200