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Mavelertinib [1776112-90-3] [1776112-90-3]

Mavelertinib [1776112-90-3] [1776112-90-3]

T21322
TargetMol Chemicals
CAS Number1776112-90-3
Product group Chemicals
Estimated Purity≥98%
Molecular Weight415.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Mavelertinib [1776112-90-3] [1776112-90-3]
  • Delivery Days Customer
    10
  • CAS Number
    1776112-90-3
  • Certification
    Research Use Only
  • Chemical Name
    Mavelertinib
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C18H22FN9O2
  • Molecular Weight
    415.42
  • Scientific Description
    Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kina
  • Shelf life instruction
    3 years
  • SMILES
    COc1nn(C)cc1Nc1nc(nc2n(C)cnc12)N1C[C@@H](F)[C@@H](C1)NC(=O)C=C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
    Read this paper