MB710

MedChem Express

MB710 [2230044-57-0]

10

2230044-57-0

Research Use Only

98.76

C16H16IN3O3S

457.29

MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C . MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C , with a K d of 4.1?microM. MB710 shows anticancer activity in p53-Y220C cell lines [1] .

O=C(C1=C2N=C(N(CC)CC)SC2=C(N3C=CC=C3)C(I)=C1O)O

-20°C,2°C to 8°C

12352200