MB710 [2230044-57-0]

TargetMol Chemicals

MB710 [2230044-57-0]

114

2230044-57-0

Chemical

Research Use Only

MB710

C16H16IN3O3S

457.29

MB710, an aminobenzothiazole derivative, stabilizes the oncogenic p53 mutation Y220C by binding tightly to the Y220C pocket, enhancing the stability of p53-Y220C with a dissociation constant (Kd) of 4.1 microM. This compound exhibits anticancer activity in cell lines harboring the p53-Y220C mutation [1].

3 years

CCN(CC)c1nc2c(C(O)=O)c(O)c(I)c(-n3cccc3)c2s1

-20°C

12352200