MBD1 antibody - ChIP grade

GeneTex

MBD1 antibody - ChIP grade

9

WB: 1:500. ELISA: 1:1,000. ChIP assay: 1-5 microg. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

MBD1

methyl-CpG binding domain protein 1

CXXC3, PCM1, RFT, methyl-CpG-binding domain protein 1, CXXC-type zinc finger protein 3, protein containing MBD 1, protein containing methyl-CpG-binding domain 1, the regulator of fibroblast growth factor 2 (FGF-2) transcription

Rabbit

IgG

Methyl-CpG-binding domain protein 1

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]

Human, Mouse

-20°C or -80°C,2°C to 8°C

41116161