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Western blot analysis of extracts of various cell lines using Myelin Basic protein Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using Myelin Basic protein Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using Myelin Basic protein Polyclonal Antibody at dilution of 1:1000.

MBP Polyclonal Antibody

Research Use Only
E-AB-60400
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    MBP Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called Golli-MBP) that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
  • UNSPSC
    12352203