MBTPS1 antibody [C1C3]

GeneTex

MBTPS1 antibody [C1C3]

9

Western Blot

Research Use Only

Polyclonal

0.89 mg/ml

Unconjugated

MBTPS1

membrane bound transcription factor peptidase, site 1

endopeptidase S1P; membrane-bound transcription factor site-1 protease; PCSK8; proprotein convertase subtilisin/kexin type 8; S1P; SEDKF; site-1 protease; SKI-1; subtilisin/kexin isozyme-1

Rabbit

IgG

Membrane-bound transcription factor site-1 protease

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203