MBTPS1 antibody

GeneTex

MBTPS1 antibody

9

WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

MBTPS1

membrane bound transcription factor peptidase, site 1

endopeptidase S1P; membrane-bound transcription factor site-1 protease; PCSK8; proprotein convertase subtilisin/kexin type 8; S1P; SEDKF; site-1 protease; SKI-1; subtilisin/kexin isozyme-1

Rabbit

IgG

Membrane-bound transcription factor site-1 protease

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

-20°C or -80°C,2°C to 8°C

12352203