![IHC-P analysis of ovarian cancer tissue using GTX60520 MCM2 antibody [1E7]. IHC-P analysis of ovarian cancer tissue using GTX60520 MCM2 antibody [1E7].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_IHC-P_1_w_23061123_716.webp)
IHC-P analysis of ovarian cancer tissue using GTX60520 MCM2 antibody [1E7].
MCM2 antibody [1E7]
GTX60520
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMCM2
Overview
- SupplierGeneTex
- Product NameMCM2 antibody [1E7]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- ConjugateUnconjugated
- Gene ID4171
- Target nameMCM2
- Target descriptionminichromosome maintenance complex component 2
- Target synonymsBM28, CCNL1, CDCL1, D3S3194, DFNA70, MITOTIN, cdc19, DNA replication licensing factor MCM2, cell devision cycle-like 1, cyclin-like 1, minichromosome maintenance deficient 2 (mitotin), minichromosome maintenance protein 2 homolog, nuclear protein BM28
- HostMouse
- IsotypeIgG1
- Protein IDP49736
- Protein NameDNA replication licensing factor MCM2
- Scientific DescriptionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of colon cancer tissue using GTX60520 MCM2 antibody [1E7]. IHC-P analysis of colon cancer tissue using GTX60520 MCM2 antibody [1E7].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_IHC-P_w_23061123_450.webp)
![FACS analysis of Jurkat cells using GTX60520 MCM2 antibody [1E7]. Green : MCM2 Red : negative control FACS analysis of Jurkat cells using GTX60520 MCM2 antibody [1E7]. Green : MCM2 Red : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_FACS_w_23061123_975.webp)
![ELISA analysis of antigen using GTX60520 MCM2 antibody [1E7].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng ELISA analysis of antigen using GTX60520 MCM2 antibody [1E7].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_ELISA_w_23061123_775.webp)
![WB analysis of MCF-7 (1), HeLa (2), Jurkat (3), K562 (4), HEK293 (5) and HepG2 (6) cell lysate using GTX60520 MCM2 antibody [1E7]. WB analysis of MCF-7 (1), HeLa (2), Jurkat (3), K562 (4), HEK293 (5) and HepG2 (6) cell lysate using GTX60520 MCM2 antibody [1E7].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_WB_1_w_23061123_926.webp)
![WB analysis of human MCM2 (AA: 16-232) recombinant protein using GTX60520 MCM2 antibody [1E7]. WB analysis of human MCM2 (AA: 16-232) recombinant protein using GTX60520 MCM2 antibody [1E7].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_WB_w_23061123_776.webp)
![ICC/IF analysis of HeLa cells using GTX60520 MCM2 antibody [1E7]. Green : MCM2 Red: Actin filaments ICC/IF analysis of HeLa cells using GTX60520 MCM2 antibody [1E7]. Green : MCM2 Red: Actin filaments](https://www.genetex.com/upload/website/prouct_img/normal/GTX60520/GTX60520_20170912_ICCIF_w_23061123_666.webp)

![IHC-P analysis of human colonic crypts tissue using GTX04968 MCM2 antibody [MSVA-502R] HistoMAX?. MCM2 staining is strongest in epithelial cells of colonic crypts. Some lymphocytes are also positive scaled.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04968/GTX04968_20241028_IHC-P_24102820_901.webp)

![IHC-P analysis of colon cancer tissue using GTX60491 MCM2 antibody [2B3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60491/GTX60491_20170912_IHC-P_w_23061123_117.webp)
![IHC-P analysis of human tonsil tissue using GTX75459 MCM2 antibody [CRCT2.1 (D1.9H5)].](https://www.genetex.com/upload/website/prouct_img/normal/GTX75459/GTX75459_4902_IHC-P_w_23051501_670.webp)


