GTX110241 IHC-P Image
GTX110241 IHC-P Image
MCM3 antibody
GTX110241
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameMCM3 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.71 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A heterogeneous cellular response to ionizing radiation revealed by single cell transcriptome sequencing. Gao Y et al., 2021, Am J Cancer ResRead more
- A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat MethodsRead more
- Function of gold nanoparticles in oral cancer beyond drug delivery: Implications in cell apoptosis. Essawy MM et al., 2021 Mar, Oral DisRead more
- Histone demethylase Kdm4b functions as a co-factor of C/EBPbeta to promote mitotic clonal expansion during differentiation of 3T3-L1 preadipocytes. Guo L et al., 2012 Dec, Cell Death DifferRead more