
WB analysis of HeLa and 293T cell lysate prepared by NETN lysis buffer using GTX24460 MCM3 antibody. Dilution : 0.1 microg/ml Loading : 50microg
MCM3 antibody
GTX24460
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Xenopus
TargetMCM3
Overview
- SupplierGeneTex
- Product NameMCM3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000 - 1:10000. IHC-P: 1:1000 - 1:5000. IP: 2 - 5 microg/mg lysate. PLA: 1:2000 - 1:40000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4172
- Target nameMCM3
- Target descriptionminichromosome maintenance complex component 3
- Target synonymscervical cancer proto-oncogene 5; DNA polymerase alpha holoenzyme-associated protein P1; DNA replication factor MCM3; DNA replication licensing factor MCM3; HCC5; hRlf beta subunit; MCM3 minichromosome maintenance deficient 3; minichromosome maintenance deficient 3; P1.h; p102; P1-MCM3; replication licensing factor, beta subunit; RLF subunit beta; RLFB
- HostRabbit
- IsotypeIgG
- Protein IDP25205
- Protein NameDNA replication licensing factor MCM3
- Scientific DescriptionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]
- ReactivityHuman, Xenopus
- Storage Instruction2°C to 8°C
- UNSPSC12352203