MCM3 Polyclonal Antibody

Elabscience

MCM3 Polyclonal Antibody

12

Western Blot

ELISA WB IHC

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

MCM3

minichromosome maintenance complex component 3

HCC5, P1-MCM3, P1.h, RLFB, DNA replication licensing factor MCM3, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, MCM3 minichromosome maintenance deficient 3, RLF subunit beta, cervical cancer proto-oncogene 5, hRlf beta subunit, minichromosome maintenance deficient 3, p102, replication licensing factor, beta subunit

Rabbit

IgG

DNA replication licensing factor MCM3

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

-20°C

41116161