Western Blot analysis of HepG2 cell using MCM3 Polyclonal Antibody at dilution of 1:500
Western Blot analysis of HepG2 cell using MCM3 Polyclonal Antibody at dilution of 1:500
MCM3 Polyclonal Antibody
E-AB-40230
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMCM3 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203