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MCP-1/CCL2, Human

HY-P7237
MedChem Express
Protein IDP13500
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MCP-1/CCL2, Human
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    98.00
  • Gene ID6347
  • Target name
    CCL2
  • Target description
    C-C motif chemokine ligand 2
  • Target synonyms
    C-C motif chemokine 2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; HSMCR30; MCAF; MCP1; MCP-1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; monocyte chemotactic protein 1; monocyte secretory protein JE; SCYA2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small-inducible cytokine A2; SMC-CF
  • Protein IDP13500
  • Protein Name
    C-C motif chemokine 2
  • Scientific Description
    MCP-1/CCL2 Protein, Human is a cytokine belonging to the CC chemokine family that interacts with the CCR2 chemokine receptor on the cell surface to mediate inflammatory immune responses, viral infections, and tumorigenesis. MCP-1/CCL2 Protein MCP-1/CCL2 Protein, Human is a recombinant human MCP-1/CCL2(Q24-T99) expressed by E.coil[1].
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100

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The chemotactic effect of GTX00415-pro Human MCP1 / CCL2 protein (active). Upper: (A) THP-1 cells were seeded into the upper chambers and serum free RPMI-1640 without MCP-1 was added in lower chamber, then cells in lower chamber were observed at low magnification (x100) after incubation for 3hrs. (B) THP-1 cells were seeded into the upper chambers and serum free RPMI-1640 with 25 ng/ml MCP-1 was added in lower chamber, then cells in lower chamber were observed at low magnification (x100) after incubation for 3hrs. (C) THP-1 cells were seeded into the upper chambers and serum free RPMI-1640 with 50 ng/ml MCP-1 was added in lower chamber, then cells in lower chamber were observed at low magnification (x100) after incubation for 3hrs. Lower: The number of migrated cells were counted at high magnification (x400) randomly (five fields for each filter).
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