MCP2 antibody [35509.11]

GeneTex

MCP2 antibody [35509.11]

9

Neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.

WB: 1-2 microg/ml. ELISA: 2.0 microg/ml. Neutralizing/Inhibition: 1-4 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

35509.11

Unconjugated

CCL8

C-C motif chemokine ligand 8

C-C motif chemokine 8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; monocyte chemoattractant protein 2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8

Mouse

IgG1

C-C motif chemokine 8

MCP2 and MCP3 are members of the C-C, or beta chemokine class. Other chemokines in this group include C10, Eotaxin, HCC1, I309, JE, MCP1, MIP1 alpha, MIP1 beta and RANTES. These chemokines act primarily as chemoattractants and antibody does not cross-react with other activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. MCP2 and MCP3 were originally identified as monocyte chemotactic proteins produced by human MG63 osteosacrcoma cells. MCP2 and MCP3 are approximately 9 kD polypeptides of 76 amino acids. MCP2 shares 62% amino acid sequence homology with MCP1, MCP3 shares 71% homology with MCP1, and MCP2 shares 58% homology with MCP3.

Human

-20°C or -80°C,2°C to 8°C

12352203