MDC antibody

GeneTex

MDC antibody

9

The antibody shows 20% cross-reactivity with recombinant human MPIF-1, 10% cross-reactivity with recombinant human MIP-1δ and 1% cross-reactivity with recombinant mouse MDC, human HCC-1, human I-309, mouse MIP-1α, viral MIP-I, mouse MIP-1β

WB: 0.1-0.2 microg/ml. ELISA: 0.5-1.0 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

CCL22

C-C motif chemokine ligand 22

A-152E5.1; ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; chemokine (C-C motif) ligand 22; DC/B-CK; macrophage-derived chemokine; MDC; MDC(1-69); SCYA22; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; STCP-1; stimulated T cell chemotactic protein 1

Chicken

IgY

C-C motif chemokine 22

MDC is a member of the beta (CC) chemokine family and induces chemotaxis or calcium mobilization in dendritic cells, IL-2 activated cells and activated T lymphocytes. MDC, also named stimulated T cell chemotactic protein (STCP-1), was isolated from clones of monocyted-derived macrophages and binds to CC chemokine receptor 4 (CCR4). MDC shows less than 35% identity to other C-C chemokine family members. It is expressed in dendritic cells, macrophages and activated monocytes. Expression is also detected in the tissues of thymus, lymph node and appendix. NH2- terminally truncated forms of natural MDC were isolated from a CD8+ T cell clone and have been reported to inhibit HIV-1 infection.

Human

-20°C or -80°C,2°C to 8°C

12352203