MDC antibody

GeneTex

MDC antibody

9

WB: 0.1-0.2 microg/ml. ELISA: 0.5-1.0 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

CCL22

C-C motif chemokine ligand 22

A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1, C-C motif chemokine 22, CC chemokine STCP-1, MDC(1-69), chemokine (C-C motif) ligand 22, macrophage-derived chemokine, small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), member 22, stimulated T cell chemotactic protein 1

Chicken

IgY

C-C motif chemokine 22

MDC is a member of the beta (CC) chemokine family and induces chemotaxis or calcium mobilization in dendritic cells, IL-2 activated cells and activated T lymphocytes. MDC, also named stimulated T cell chemotactic protein (STCP-1), was isolated from clones of monocyted-derived macrophages and binds to CC chemokine receptor 4 (CCR4). MDC shows less than 35% identity to other C-C chemokine family members. It is expressed in dendritic cells, macrophages and activated monocytes. Expression is also detected in the tissues of thymus, lymph node and appendix. NH2- terminally truncated forms of natural MDC were isolated from a CD8+ T cell clone and have been reported to inhibit HIV-1 infection.

-20°C or -80°C,2°C to 8°C

12352203