MDC antibody

GeneTex

MDC antibody

9

WB: Use at a dilution of 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Rabbit

IgG

MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a NH2-terminalsequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages (ref 1). Recombinant MDC attracts monocyte-derived dendritic cells, activated lymphocytes and natural killer cells (ref 1,2). MDC has anti-HIV-1 activity (ref 2). Expression of MDC mRNA in macrophages is enhanced by LPS, IL-1 and TNF (ref 3). MDC is a functional ligand for CCR4 (ref 4).

Rat

-20°C or -80°C,2°C to 8°C

12352203