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MEG (hemisulfate) [3979-00-8]

HY-138454
MedChem Express
CAS Number3979-00-8
Product group Chemicals
Molecular Weight168.23
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MEG (hemisulfate) [3979-00-8]
  • Delivery Days Customer
    10
  • CAS Number
    3979-00-8
  • Certification
    Research Use Only
  • Molecular Formula
    C3H9N3S.1/2H2O4S
  • Molecular Weight
    168.23
  • Scientific Description
    MEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 microM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock[1][2][3][4].
  • SMILES
    NC(NCCS)=N.O=S(O)(O)=O.[1/2]
  • UNSPSC
    12131703

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