MEG (hemisulfate) [3979-00-8]
HY-138454
Overview
- SupplierMedChem Express
- Product NameMEG (hemisulfate) [3979-00-8]
- Delivery Days Customer10
- CAS Number3979-00-8
- CertificationResearch Use Only
- Molecular FormulaC3H9N3S.1/2H2O4S
- Molecular Weight168.23
- Scientific DescriptionMEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 microM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock[1][2][3][4].
- SMILESNC(NCCS)=N.O=S(O)(O)=O.[1/2]
- UNSPSC12131703