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MEG hemisulfate [3979-00-8]
T21967
Overview
- SupplierTargetMol Chemicals
- Product NameMEG hemisulfate [3979-00-8]
- Delivery Days Customer9
- CAS Number3979-00-8
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameMEG hemisulfate
- Estimated Purity98.09%
- Molecular FormulaC6H20N6O4S3
- Molecular Weight336.44
- Scientific DescriptionMEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 microM for iNOS, 110 microM for ecNOS, and 60 microM for bNOS in tissue homogenates. It is notably effective as a peroxynitrite scavenger and blocks peroxynitrite-triggered oxidative mechanisms. Furthermore, this compound offers protective benefits across various experimental inflammation prototypes, such as ischemia/reperfusion injury, hemorrhagic shock, periodontitis, inflammatory bowel disease, and both endotoxic and septic shock.
- Shelf life instruction3 years
- SMILESO=S(O)(O)=O.N=C(NCCS)N.N=C(NCCS)N
- Storage Instruction-20°C
- UNSPSC12352200