MEK1 antibody
GTX102391
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMAP2K1
Overview
- SupplierGeneTex
- Product NameMEK1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5604
- Target nameMAP2K1
- Target descriptionmitogen-activated protein kinase kinase 1
- Target synonymsCFC3, MAPKK1, MEK1, MEL, MKK1, PRKMK1, dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAPK/ERK kinase 1, MAPKK 1, MEK 1, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)
- HostRabbit
- IsotypeIgG
- Protein IDQ02750
- Protein NameDual specificity mitogen-activated protein kinase kinase 1
- Scientific DescriptionThe protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Jeon JH, Oh TR, Park S, et al. The Antipsychotic Drug Clozapine Suppresses the RGS4 Polyubiquitylation and Proteasomal Degradation Mediated by the Arg/N-Degron Pathway. Neurotherapeutics. 2021,18(3):1768-1782. doi: 10.1007/s13311-021-01039-0Read this paper
- Tang WF, Huang RT, Chien KY, et al. Large-Scale Proteomic Identification of Targets of Cellular miR-197 Downregulated by Enterovirus A71. J Proteome Res. 2019,18(1):449-460. doi: 10.1021/acs.jproteome.8b00762Read this paper
- Wang TH, Hsueh C, Chen CC, et al. Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction. Int J Mol Sci. 2018,19(9). doi: 10.3390/ijms19092687Read this paper





![ICC/IF analysis of C6 cells using GTX01293 MEK1 antibody [GT1158]. Orange: Primary antibody Blue: DAPI](https://www.genetex.com/upload/website/prouct_img/normal/GTX01293/GTX01293_20191101_AP_002_69_w_23053121_682.webp)
![WB analysis of HEK293T cells transfected with MEK1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84168 MEK1 antibody [1C1]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84168/GTX84168_4172_WB_w_23061420_362.webp)
