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Metformin (hydrochloride)

HY-17471A
MedChem Express
CAS Number1115-70-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.95
Molecular Weight165.62
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Metformin (hydrochloride) [1115-70-4]
  • Delivery Days Customer
    10
  • CAS Number
    1115-70-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C4H12ClN5
  • Molecular Weight
    165.62
  • Scientific Description
    Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, metformin hydrochloride regulates the expression of autophagy -related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo [1] [2] [3] [4] [5] [6] [7] .
  • SMILES
    NC(NC(N(C)C)=N)=N.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200