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MI-3454 [2134169-43-8]

MI-3454 [2134169-43-8]

T39584
TargetMol Chemicals
CAS Number2134169-43-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.68%
Molecular Weight636.73
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    MI-3454 [2134169-43-8]
  • Delivery Days Customer
    10
  • CAS Number
    2134169-43-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    MI-3454
  • Estimated Purity
    99.68%
  • Molecular Formula
    C32H35F3N8OS
  • Molecular Weight
    636.73
  • Scientific Description
    MI-3454 is an orally active, selective and potent inhibitor of Menin-MLL1 interaction that inhibits the proliferation and induces differentiation of acute leukemia cells with MLL1 translocation or NPM1 mutation.MI-3454 induces complete remission or regression of leukemia in a mouse model of leukemia with MLL1 rearrangement or NPM1 mutation through the down-regulation of key genes involved in leukemogenesis. complete remission or remission.
  • Shelf life instruction
    3 years
  • SMILES
    CNc1nc(NC2CCN(Cc3ccc4n(CC56CC(C5)(C6)NC=O)c(cc4c3C)C#N)CC2)c2cc(CC(F)(F)F)sc2n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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