Western blot analysis of extracts of various cell lines using MICA Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using MICA Polyclonal Antibody at dilution of 1:1000.
MICA Polyclonal Antibody
E-AB-60301
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMICA Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
- UNSPSC12352203