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MICU2 Antibody, HRP conjugated

Research Use Only
CSB-PA818265LB01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetMICU2
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More than 130 suppliers
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Overview

  • Supplier
    Cusabio
  • Product Name
    MICU2 Antibody, HRP conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    HRP
  • Gene ID221154
  • Target name
    MICU2
  • Target description
    mitochondrial calcium uptake 2
  • Target synonyms
    1110008L20Rik; calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; EFHA1; EF-hand domain-containing family member A1; Smhs2 homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8IYU8
  • Protein Name
    Calcium uptake protein 2, mitochondrial
  • Scientific Description
    Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203