Migalastat [108147-54-2]
HY-14929
Overview
- SupplierMedChem Express
- Product NameMigalastat [108147-54-2]
- Delivery Days Customer10
- CAS Number108147-54-2
- CertificationResearch Use Only
- Molecular FormulaC6H13NO4
- Molecular Weight163.17
- Scientific DescriptionMigalastat (GR181413A free base) is an orally active alpha-galactosidase A molecular chaperone, with an IC50 value of 0.04 microM for human alpha-Gal A. Migalastat binds to the active site of certain unstable mutant forms of alpha-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant alpha-galactosidase A to exhibit biological activity[1].
- SMILESO[C@H]1[C@@H](CO)NC[C@H](O)[C@H]1O
- UNSPSC12131703