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Migalastat [108147-54-2]

HY-14929
MedChem Express
CAS Number108147-54-2
Product group Chemicals
Molecular Weight163.17
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Migalastat [108147-54-2]
  • Delivery Days Customer
    10
  • CAS Number
    108147-54-2
  • Certification
    Research Use Only
  • Molecular Formula
    C6H13NO4
  • Molecular Weight
    163.17
  • Scientific Description
    Migalastat (GR181413A free base) is an orally active alpha-galactosidase A molecular chaperone, with an IC50 value of 0.04 microM for human alpha-Gal A. Migalastat binds to the active site of certain unstable mutant forms of alpha-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant alpha-galactosidase A to exhibit biological activity[1].
  • SMILES
    O[C@H]1[C@@H](CO)NC[C@H](O)[C@H]1O
  • UNSPSC
    12131703

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