Miransertib (hydrochloride)

MedChem Express

Miransertib (hydrochloride) [1313883-00-9]

10

1313883-00-9

Research Use Only

99.74

C27H25ClN6

468.98

Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1] . Miransertib hydrochloride is effective against Leishmania [2] .

NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5.[H]Cl

-20°C,2°C to 8°C

12352200