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ProductsBack/Miransertib hydrochloride

Miransertib hydrochloride

M11229

CAS Number1313883-00-9

Product group Chemicals

Molecular Weight468.99

Overview

Supplier
AbMole BioScience
Product Name
Miransertib hydrochloride
Delivery Days Customer
9
CAS Number
1313883-00-9
Category Supplier
Chemical
Certification
Research Use Only
Molecular Formula
C27H25ClN6
Molecular Weight
468.99
Scientific Description
Miransertib hydrochloride (ARQ-092 Hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with an IC50 of 2.7 nM for Akt1, Akt2, and Akt3, respectively. 14 nM and 8.1 nM. Miransertib hydrochloride is an effective inhibitor of AKT1-E17K mutant protein, and can be used in the study of PI3K/ AkT-driven tumors and Proteus syndrome. Miransertib hydrochloride effectively inhibited Leishmania.
SMILES
Cl.NC1=NC=CC=C1C2=NC3=CC=C(N=C3[N]2C4=CC=C(C=C4)C5(N)CCC5)C6=CC=CC=C6
UNSPSC
12352200

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