Mirk-IN-1

Biorbyt

Mirk-IN-1 [1386979-55-0]

10

1386979-55-0

Research Use Only

C23H17CL2N5O4

498.3182

Mirk-IN-1 is a potent, specific inhibitor of Dyrk1B (Mirk kianse) and Dyrk1A with IC50 of 68 nM and 22 nM respectively, shows SW620 cell IC50 of 1.9 uM.

ClC1C([H])=C([H])C(C(N([H])C([H])([H])C2C([H])=C([H])C([H])=C(C=2[H])Cl)=O)=C([H])C=1N([H])C(C1C(N([H])C2C(=C([H])N=C(N=2)OC([H])([H])[H])C=1[H])=O)=O

12352200