ICC/IF analysis of mouse melanoma B16 cells using GTX00738 MITF antibody. Green : Primary antibody Blue : DAPI Dilution : 1:1000 Fixation : 4% PFA Permeabilization : 0.25 % Triton X-100

MITF antibody

GTX00738

ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetMITF

Overview

Supplier
GeneTex
Product Name
MITF antibody - KO/KD Validated
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:3000. IHC-P: 1:300-1:1000. IHC-Fr: 1:300-1:1000. ChIP assay: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID4286
Target name
MITF
Target description
melanocyte inducing transcription factor
Target synonyms
bHLHe32; class E basic helix-loop-helix protein 32; CMM8; COMMAD; melanogenesis associated transcription factor; MI; microphtalmia-associated transcription factor; microphthalmia-associated transcription factor; MITF-A; WS2; WS2A
Host
Rabbit
Isotype
IgG
Protein IDO75030
Protein Name
Microphthalmia-associated transcription factor
Scientific Description
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Hseu YC et al., 2021 Aug, Redox Biol
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MITF antibody

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Overview

References

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