MK-2206 [1032349-77-1]

TargetMol Chemicals

MK-2206 [1032349-77-1]

72

1032349-77-1

Research Use Only

MK-2206

C25H22ClN5O

443.94

MK-2206 is an orally active, highly selective, metabotropic Akt inhibitor that targets Akt1 [IC50: 8 nM], Akt2 [IC50: 12 nM], and Akt3 [IC50: 65 nM]. Many breast cancer cell lines, PIK3CA mutants, and PTEN-losing cell lines are sensitive to MK-2206, which exhibits anti-cancer effects.

3 years

Cl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1

-20°C

12352200