MMAF intermediate 2 [864238-20-0]

MedChem Express

MMAF intermediate 2 [864238-20-0]

14

864238-20-0

Research Use Only

99.77

C19H29ClN2O4

384.90

MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1].

O=C(N[C@H](C(OC)=O)CC1=CC=CC=C1)[C@H](C)[C@@H](OC)[C@H]2NCCC2.Cl

2°C to 8°C

12352200