MMAF intermediate 2 [864238-20-0]

TargetMol Chemicals

MMAF intermediate 2 [864238-20-0]

9

864238-20-0

Research Use Only

C19H29ClN2O4

384.9

MMAFintermediate 2 serves as a precursor in the synthesis of MMAF (Monomethylauristatin F). MMAF is a potent inhibitor of tubulin polymerization and a cytotoxic component of classical antibody-drug conjugates (ADCs), including Vorsetuzumab mafodotin and SGN-CD19A, serving as the ADC Cytotoxin.

[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O)C)(OC)[C@@]2(CCCN2)[H].Cl

-20°C

12352200