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Western Blot analysis of HT-29 cells using MMP2 Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of HT-29 cells using MMP2 Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of HT-29 cells using MMP2 Polyclonal Antibody at dilution of 1:1000.

MMP-2 Polyclonal Antibody

Research Use Only
E-AB-32054
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    MMP-2 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    WB,IHC,IF,ELISA
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Scientific Description
    Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
  • UNSPSC
    12352203