ICC/IF analysis of formalin-fixed MCF7 cells using GTX00674 MMP1 antibody. Red : Primary antibody Blue : DAPI Perrmeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
ICC/IF analysis of formalin-fixed MCF7 cells using GTX00674 MMP1 antibody. Red : Primary antibody Blue : DAPI Perrmeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
MMP1 antibody
GTX00674
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMMP1
Overview
- SupplierGeneTex
- Product NameMMP1 antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4312
- Target nameMMP1
- Target descriptionmatrix metallopeptidase 1
- Target synonymsCLG; CLGN; fibroblast collagenase; interstitial collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Cutaneous Regeneration Mechanism of beta-Sheet Silk Fibroin in a Rat Burn Wound Healing Model. Chou KC et al., 2021 Oct 14, Polymers (Basel)Read more
- Inhibition of CD44 induces apoptosis, inflammation, and matrix metalloproteinase expression in tendinopathy. Wu PT et al., 2019 Dec 27, J Biol ChemRead more