MMP1 antibody
GTX100534
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMMP1
Overview
- SupplierGeneTex
- Product NameMMP1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.54 mg/ml
- ConjugateUnconjugated
- Gene ID4312
- Target nameMMP1
- Target descriptionmatrix metallopeptidase 1
- Target synonymsCLG, CLGN, interstitial collagenase, fibroblast collagenase, matrix metallopeptidase 1 (interstitial collagenase), matrix metalloprotease 1
- HostRabbit
- IsotypeIgG
- Protein IDP03956
- Protein NameInterstitial collagenase
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Guo Y, Chomiak AA, Hong Y, et al. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration. iScience. 2022,25(7):104519. doi: 10.1016/j.isci.2022.104519Read this paper
- Jeon S, Yoon YS, Kim HK, et al. Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway. Aging (Albany NY). 2021,13(5):6406-6419. doi: 10.18632/aging.202744Read this paper
- Mandal JP, Shiue CN, Chen YC, et al. PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression. Free Radic Biol Med. 2021,163:69-87. doi: 10.1016/j.freeradbiomed.2020.12.003Read this paper
- Lee KE, Bharadwaj S, Yadava U, et al. Computational and In Vitro Investigation of (-)-Epicatechin and Proanthocyanidin B2 as Inhibitors of Human Matrix Metalloproteinase 1. Biomolecules. 2020,10(10). doi: 10.3390/biom10101379Read this paper
- Mahdavi N, Aminishakib P, Nabiyi P, et al. Evaluation of the presence of myofibroblasts and matrix metalloproteinase 1 expression in the stroma of oral verrucous hyperplasia and verrucous carcinoma. Indian J Pathol Microbiol. 2020,63(3):369-375. doi: 10.4103/IJPM.IJPM_548_19Read this paper
- Wang C, Chi Q, Sha Y, et al. Mechanical injury and IL-1β regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Biotechnol Lett. 2020,42(8):1567-1579. doi: 10.1007/s10529-020-02870-9Read this paper
- Wu PY, Lin TY, Hou CW, et al. 1,2-Bis[(3-Methoxyphenyl)Methyl]Ethane-1,2-Dicarboxylic Acid Reduces UVB-Induced Photodamage In Vitro and In Vivo. Antioxidants (Basel). 2019,8(10). doi: 10.3390/antiox8100452Read this paper
- Bordignon P, Bottoni G, Xu X, et al. Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant. Cell Rep. 2019,28(9):2358-2372.e6. doi: 10.1016/j.celrep.2019.07.092Read this paper
- Dubey NK, Wei HJ, Yu SH, et al. Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade. Aging Dis. 2019,10(3):483-496. doi: 10.14336/AD.2018.0616Read this paper
- Liu J, Cao L, Zhao N, et al. miR‑338‑3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and β‑catenin signaling pathways. Mol Med Rep. 2019,20(1):33-40. doi: 10.3892/mmr.2019.10215Read this paper
Datasheet
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